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宫腔镜电凝辅助宫颈冷刀锥切术在宫颈上皮内瘤样病变诊断中的价值研究 被引量:2

Value of Hysteroscopic Coagulation Assisted with Cervical Cold Knife Conization in the Diagnosis of Cervical Intraepithelial Neoplasia
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摘要 目的:探讨宫腔镜电凝辅助宫颈冷刀锥切术在宫颈上皮内瘤样病变(CIN)的诊疗价值。方法:回顾性分析某院2016年1月~2017年1月收治的120例CIN患者的临床资料,依据是否采用宫腔镜电凝辅助将以上研究对象分为宫腔镜组(70例)和锥切术组(50例),锥切术组予以传统的宫颈冷刀锥切术,宫腔镜组予以宫腔镜电凝辅助宫颈冷刀锥切术,比较两组的术中出血量、手术时间、住院时间等围手术期指标、术后病理符合及切缘病变残留情况、术后高危HPV转阴情况以及并发症情况。结果:宫腔镜组的术中出血量、手术时间及住院时间均显著短于锥切术组(P<0.05);宫腔镜组的术后病理符合率显著高于锥切术组(P<0.05),切缘病变残留率显著低于锥切术组(P<0.05);宫腔镜组与锥切术组术后3个月及术后6个月的高危HPV转阴率比较无显著差异(P>0.05),宫腔镜组术后9个月的HPV转阴率显著高于锥切术组(P<0.05);宫腔镜组的并发症发生率(4.29%)显著低于锥切术组(16.00%)(P<0.05)。结论:与传统宫颈锥切术比较,宫腔镜电凝辅助宫颈冷刀锥切术诊疗CIN具有出血少、手术时间短、术后HPV转阴率高等优点。 Objective:To explore the diagnosis and treatment value of hysteroscopic coagulation assisted with cervical cold knife conization on cervical intraepithelial neoplasia(CIN).Methods:The clinical data of 120patients with CIN admitted to a hospital from January 2016to January 2017were retrospectively analyzed.The above subjects were divided into hysteroscopic group(70cases)and conization(50cases)according to whether hysteroscopic coagulation was used or not.Conization group was treated with traditional cervical cold knife conization,and hysteroscopic group was given hysteroscopic coagulation assisted with cervical cold knife conization.The perioperative indicators of intraoperative blood loss,operative time and hospital stay,postoperative pathological coincidence and incisor margin residual lesions,postoperative high-risk HPV negative conversion and complications were compared between the two groups.Results:The intraoperative blood loss,operative time and hospital stay in hysteroscopic group were significantly shorter than those in conization group(P<0.05).The postoperative pathological coincidence rate in hysteroscopic group was significantly higher than that in conization group(P<0.05),the residual rate of incisor margin lesions was significantly lower than that in conization group(P<0.05).There was no significant difference in the high-risk HPV negative conversion rate between hysteroscopic group and conization group at 3months and 6months after operation(P>0.05),and the HPV negative conversion rate in hysteroscopic group was significantly higher than that in conization group(P<0.05).The incidence rate of complications in hysteroscopic group was significantly lower than that in conization group(4.29%vs 16.00%)(P<0.05).Conclusion:Compared with traditional cervical conization,hysteroscopic coagulation assisted with cervical cold knife conization has the advantages of less bleeding,shorter operative time and higher postoperative HPV negative conversion rate in the diagnosis and treatment of CIN.
作者 朱辛茹 李宁 Zhu Xinru;Li Ning(Department of Obstetrics and Gynecology,Henan Provincial No.3 People's Hospital,Zhengzhou 450006)
出处 《数理医药学杂志》 2020年第1期1-3,共3页 Journal of Mathematical Medicine
关键词 宫腔镜 电凝 宫颈冷刀锥切术 宫颈上皮内瘤样病变 hysteroscopic coagulation cervical cold knife conization cervical intraepithelial neoplasia
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