CuI催化下金属钐介入的查尔酮偶联与环化

CuI Catalyzed Coupling and Cyclization of Chalcones Mediated by Samarium Metal

室温条件下,10%(摩尔分数)碘化亚铜催化金属钐与查尔酮以良好的产率得到环戊醇衍生物。对反应溶剂、温度等反应条件的影响进行了研究。在优化的反应条件下,反应以51%~91%产率得到系列环戊醇衍生物。同时考察了查尔酮上不同取代基对产率的影响。给出了代表性产物的1H NMR、13 C NMR及熔点等数据表征。

Under the conditions of room temperature,the samarium metal and copper(I)iodide catalyze the chalcone to obtain a cyclopentanol derivatives in good yields(51%—91%).The reaction conditions such as solvent and temperature were optimized,and the effect of different substituents of chalcone on the yields was investigated.The paper attached 1H NMR,13 C NMR,and melting point of the main substance.