连花清瘟颗粒治疗54例新型冠状病毒肺炎患者临床分析及典型病例报道

Clinical Effectiveness and Case Analysis in 54 NCP Patients Treated with Lanhuaqingwen Granules

目的:分析连花清瘟颗粒治疗新型冠状病毒肺炎的临床疗效。方法:选取2020年1月1-31日在武汉科技大学附属普仁医院就诊的,应用连花清瘟颗粒联合常规治疗(根据病情监测给予营养支持治疗、抗病毒治疗及抗菌药物治疗等)的新型冠状病毒肺炎患者54例作为研究对象。结果:应用连花清瘟颗粒治疗3 d后,发热、乏力、咳嗽症状消失率分别为47.5%、35.1%、20.0%,治疗5 d后发热、乏力、咳嗽症状消失率分别为62.5%、59.5%、50.0%,治疗7 d后发热、乏力、咳嗽症状消失率分别为80.0%、75.7%、76.7%;发热、乏力、咳嗽消失天数分别为(3.6±2.14)d、(4.1±2.58)d、(5.3±2.63)d;治疗7 d后,其他症状体征(胸闷、呼吸困难、湿啰音)消失率分别为84.6%、100%、89.5%;有效率为81.6%,且临床应用安全性良好。结论:连花清瘟颗粒明显改善新型冠状病毒肺炎普通型患者发热、咳嗽、乏力等症状,减少发热、乏力、咳嗽持续天数,为临床治疗该病提供初步研究证据。

Objective:To analyze the clinical effectiveness of Lianhuaqingwen Granules(LH-C)novel coronavirus pneumonia(NCP)patients.Methods:The clinical data of 54 ordinary NCP patients were retrospectively analyzed at the Puren affiliated Hospital of Wuhan University of Science and Technology.Results:After treatment with LH-C for three consecutive days,the rate of symptoms disappearance in fever,weakness,and cough was 47.5%,35.1%,and 20%,respectively.Five days later,the rate of symptoms disappearance in fever,weakness,and cough increased to 62.5%,59.5%,and 50.0%,respectively.By the seventh day,the rate of symptoms disappearance in fever,weakness,and cough reached 80.0%,75.7%,and 76.7%.The days of symptoms disappearance in fever,weakness,and cough was(3.6±2.14)d,(4.1±2.58)d,and(5.3±2.63)d.As regards the other symptom,the rate of symptoms disappearance in the chest stuffiness,the dyspnea,and the moist crackles was 84.6%,100%,and 89.5%,and the total efficiency was up to 81.6% without any observed side effects by the seventh day.Conclusion:LH-C could significantly relieve clinical symptoms in ordinary NCP patients by inhibiting fever,weakness,and cough,and reducing their duration.All these results provided preliminary clinical evidence for LH-C in the NCP treatment.