孕晚期孕妇B群无乳链球菌感染情况及耐药性分析

Analysis on the Infection and Drug Resistance of Group B of Advanced Pregnant Women

目的探讨孕晚期孕妇B群无乳链球菌(GBS)感染情况及耐药性。方法选择358例孕晚期孕妇,所有孕妇泌尿生殖道样本进行GBS检测及药敏试验。结果358例孕妇中41例感染GBS,感染率为11.45%;不同类型样本中感染率最高的为阴道分泌物14.72%;不同年龄段中40~45岁孕妇感染率最高,达到14.29%;GBS对青霉素、氨苄西林、头孢曲松、万古霉素以及头孢他啶耐药性较低。结论因加强对孕晚期孕妇GBS的筛查工作,关注耐药性变化,干预药物可选用青霉素、氨苄西林以及头孢曲松。

Objective To investigate the infection and drug resistance of group B streptococcus alactis(GBS)in late-stage pregnant women.Methods GBS test and drug sensitivity test were performed in 358 women with advanced stage of pregnancy.Results 41 of the 358 pregnant women were infected with GBS,with an infection rate of 11.45%.The highest infection rate in different types of samples was 14.72%of vaginal secretions.Among different age groups,the infection rate of pregnant women between 40 and 45 years old was the highest,reaching 14.29%.Resistance of GBS to penicillin,ampicillin,ceftriaxone,vancomycin and ceftazidine was low.Conclusion Penicillin,ampicillin and ceftriaxone can be used as intervention drugs for strengthening the screening of GBS in late pregnancy and paying attention to the change of drug resistance.