腹腔镜下宫颈癌根治术联合术后辅助化疗在宫颈癌患者中的应用效果观察

Effect of laparoscopic radical resection of cervical cancer combined with postoperative adjuvant chemotherapy in patients with cervical cancer

目的判定腹腔镜下宫颈癌根治术配合术后辅助化疗运用于宫颈癌患者中效果。方法选取2014年1月至2015年1月武汉同济医院治疗的64例宫颈癌患者作为研究对象;依据抽签法分为对照组与观察组,各32例;对照组:实施传统开腹手术;观察组:实施腹腔镜下宫颈癌根治术配合术后辅助化疗;比较两组手术耗时、术中出血量、术后肛门恢复通气时间、住院天数、术后并发症合计率、术后复发合计率。结果观察组手术耗时与对照组比较差异无统计学意义,观察组术后肛门恢复通气时间、住院天数短于对照组(P<0.01),观察组术中出血量低于对照组(P<0.01);观察组术后并发症合计率低于对照组(P<0.05);观察组术后复发合计率低于对照组(P<0.05)。结论对宫颈癌患者实行腹腔镜下宫颈癌根治术配合术后辅助化疗的临床效果较优。

Objective To determine the effect of laparoscopic radical resection of cervical cancer combined with postoperative adjuvant chemotherapy in patients with cervical cancer. Methods Sixty-four patients with cervical cancer treated at Wuhan Tongji Hospital from January 2014 to January 2015 were selected as the research objects;they were divided into a control group and an observation group, each with 32 cases according to the lotterys. The control group: traditional open surgery was performed. Laparoscopic radical resection of cervical cancer combined with postoperative adjuvant chemotherapy;comparison of operation time, intraoperative blood loss, postoperative anal recovery ventilation time, hospitalization days, postoperative complications, and postoperative recurrence rate. Results There was no significant difference in the operation time of the observation group compared with the control group. The postoperative anal recovery ventilation time and hospitalization days were shorter in the observation group than in the control group(P<0.01). The intraoperative blood loss in the observation group was lower than that in the control group(P<0.01). The total postoperative complications in the observation group was lower than that in the control group(P<0.05);the total recurrence rate in the observation group was lower than that in the control group(P<0.05). Conclusion The clinical effect of laparoscopic radical resection of cervical cancer combined with postoperative adjuvant chemotherapy is superior in patients with cervical cancer.