低分子肝素钙预防老年下肢创伤骨折患者术后深静脉血栓形成的效果分析

Effect of Low Molecular Weight Heparin Calcium on Prevention of Deep Venous Thrombosis in Elderly Patients with Lower Limb Traumatic Fracture after Operation

目的:探讨低分子肝素钙预防老年下肢创伤骨折患者术后深静脉血栓形成的临床效果。方法:选择我院收治的68例老年下肢创伤骨折患者为研究对象,随机分为对照组(n=34)与观察组(n=34),其中对照组患者给予抗血小板类药物阿司匹林治疗,观察组中患者给予低分子肝素钙治疗,对比分析两组间患者在治疗后预防深静脉血栓形成的临床效果。结果:观察组中所有患者在治疗后,其下肢深静脉血栓形成占比更低于对照组,各项凝血功能指标凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)水平改善效果优于对照组,且观察组D-二聚体水平更低于对照组,两组相比差异有统计学意义(P<0.05)。结论:对老年下肢创伤骨折患者在术后给予低分子肝素钙治疗,能够明显预防下肢深静脉血栓的形成,改善其凝血功能,以促进患者尽早恢复健康。

Objective:To investigate the clinical effect of low molecular weight heparin calcium in preventing deep venous thrombosis in elderly patients with lower limb traumatic fracture after operation.Methods:68 elderly patients with lower extremity traumatic fracture were selected as the research objects.The patients were randomly divided into control group(n=34)and observation group(n=34).The patients in control group were treated with aspirin,while those in observation group were treated with low molecular weight heparin calcium.Clinical effect of prevention of deep venous thrombosis after treatment.Results:After treatment,the proportion of deep venous thrombosis in lower extremities was lower in the observation group than in the control group.The improvement effect of PT,TT,APTT and FIB was better than that in the control group,and the level of D-dimer in the observation group was lower than that in the control group.There was significant difference between the two groups(P<0.05).Conclusion:Low molecular weight heparin calcium can prevent the formation of deep venous thrombosis and improve the coagulation function in elderly patients with lower limb traumatic fracture after operation,so as to promote the recovery of patients as soon as possible.