抗生素在预防普外科手术切口感染中的应用

Application of Antibiotics in Prevention of Incision Infection in General Surgery

目的:分析抗生素在预防普外科手术切口感染中的应用效果。方法:选取2017年1月至2018年12月期间在我院普外科进行手术治疗的62例患者,随机分为A、B、C三组,其中A组20例,B组21例,C组21例。A组术前30min^1h常规使用抗生素预防性治疗直至术后体温恢复正常2~3d后停用;B组术前30min^1h常规使用抗生素预防性治疗直至术后切口基本愈合;C组术前不使用抗生素,术后常规使用抗生素预防性治疗。观察三组患者切口感染发生率。结果:A、B两组均无患者出现切口感染,C组有2例患者出现切口感染,切口感染率为9.5%,A、B两组切口感染率显著低于C组(P<0.5)。结论:抗生素预防性治疗能够有效降低普外科术后切口感染率,但要合理使用。

Objective:To analyze the effect of antibiotics in the prevention of incision infection in general surgery.Methods:From January 2017 to December 2018,62 patients in general surgery were randomly divided into three groups:A,B and C,20 in group A,21 in group B and 21 in group C.In group A,antibiotic prophylactic treatment was used 30 minutes to 1 hour before operation until the postoperative temperature returned to normal 2 to 3 days later;in group B,antibiotic prophylactic treatment was used 30 minutes to 1 hour before operation until the incision healed basically;in group C,antibiotic prophylactic treatment was not used before operation and antibiotic prophylactic treatment was used after operation.The incidence of incision infection was observed in three groups.Results:There was no incision infection in group A and B.There were 2 cases in group C,the infection rate was 9.5%.The infection rate in group A and B was significantly lower than that in group C(P<0.5).Conclusion:Antibiotic prophylactic treatment can effectively reduce the infection rate of incision after general surgery,but it should be used reasonably.