胺碘酮治疗心衰合并心律失常患者的干预研究

Intervention Study of Amiodarone in Patients with Heart Failure and Arrhythmia

目的:探讨心衰伴心律失常采用胺碘酮加胺碘酮治疗的效果。方法:将200例心衰伴心律失常患者随机分组,常规组100例患者实施常规药物治疗,观察组100例患者实施常规药物联合胺碘酮治疗。比较两组患者的治疗结果。结果:观察组患者的有效率明显高于常规组,P<0.05。观察组患者的左心室射血分数(LVEF)、Q-T平均水平以及心率(HR)均优于常规组,P<0.05。观察组患者的短阵室性心动过速消失的时间、室性早搏消失的时间、心功能进步2级时间均短于常规组,P<0.05。两组均无出现不良反应。结论:心衰伴心律失常患者实施常规药物联合胺碘酮治疗效果确切,可促进患者心功能恢复,并缩短治疗的时间,加速患者的恢复进程,且安全性高,无明显不良反应。

Objective:To investigate the effect of amiodarone plus amiodarone on heart failure with arrhythmia.Methods:200 patients with heart failure and arrhythmia were randomly divided into groups,100 patients in the conventional group were treated with conventional drugs,and 100 patients in the observation group were treated with conventional drugs combined with amiodarone.The treatment results of the two groups of patients were compared.Results:The effective rate of the observation group was significantly higher than that of the conventional group,P<0.05.The left ventricular ejection fraction(LVEF),average Q-T level,and heart rate(HR)of the observation group were better than those of the conventional group,P<0.05.The time for the disappearance of short-term ventricular tachycardia,the disappearance of ventricular premature beats,and the improvement of cardiac function level 2 in the observation group were shorter than those in the conventional group,P<0.05.No adverse reactions occurred in either group.Conclusion:Patients with heart failure and arrhythmia have regular effects of conventional drugs combined with amiodarone,which can promote the recovery of cardiac function,shorten the time of treatment,accelerate the recovery process of patients,and have high safety without obvious adverse reactions.