期刊文献+

布地奈德雾化吸入在婴幼儿肺炎支原体感染致慢性咳嗽治疗中的应用 被引量:1

Application of Budesonide Aerosol Inhalation in the Treatment of Chronic Cough Caused by Mycoplasma Pneumoniae Infection in Infants
下载PDF
导出
摘要 目的:探讨布地奈德雾化吸入在婴幼儿肺炎支原体感染致慢性咳嗽治疗中的应用。方法:选取在我院接受治疗的510例肺炎支原体感染致慢性咳嗽患儿,随机分为对照组(n=255)与观察组(n=255);两组患儿均对症治疗,对照组给予孟鲁司特治疗,观察组在此基础上加用布地奈德雾化吸入治疗,对比两种用药方法的效果。结果:观察组治疗整体有效率高于对照组(P<0.05),观察组症状开始缓解时间与症状消失时间均短于对照组(P<0.05)。结论:在婴幼儿肺炎支原体感染致慢性咳嗽的常规孟鲁司特治疗中引入布地奈德雾化吸入方案,能够提高临床治疗效果。 Objective:To explore the application of Budesonide aerosol inhalation in the treatment of chronic cough caused by Mycoplasma pneumoniae infection in infants.Methods:510 children with chronic cough caused by Mycoplasma pneumoniae infection were selected and randomly divided into control group(n=255)and observation group(n=255).Two groups of patients were treated symptomatically,while the control group was treated with montelukast.The observation group was treated with Budesonide aerosol inhalation on the basis of the control group,and the effect of the two medication methods was compared.Results:The overall effective rate of treatment in the observation group was higher than that in the control group(P<0.05),The time of symptom relief and disappearance in the observation group were shorter than those in the control group(P<0.05).Conclusion:Introducing Budesonide aerosol inhalation into routine montelukast therapy for chronic cough caused by Mycoplasma pneumoniae infection in infants can improve clinical treatment effect.
作者 池新红 CHI Xin-hong(Anyang Sixth People’s Hospital,Anyang Henan 455000,China)
出处 《药品评价》 CAS 2019年第22期9-9,13,共2页 Drug Evaluation
关键词 布地奈德雾化吸入 婴幼儿 慢性咳嗽 肺炎支原体感染 Budesonide Aerosol Inhalation Infants Chronic Cough Mycoplasma Pneumoniae Infection
  • 相关文献

二级参考文献55

  • 1蒋文丽.用阿奇霉素联合头孢曲松钠治疗小儿重症支原体肺炎的疗效观察[J].当代医药论丛,2014,12(8):239-241. 被引量:7
  • 2钟南山,赖克方.咳嗽的诊断与治疗指南(草案)[J].诊断学理论与实践,2006,5(2):187-192. 被引量:35
  • 3无.儿童社区获得性肺炎管理指南(试行)(下)[J].中华儿科杂志,2007,45(3):223-230. 被引量:208
  • 4胡亚美,江载芳.诸福堂实用儿科学.第7版.北京:人民出版社.2002.1167.
  • 5Chu HW, Campbell JA, Harbeck RJ, et al. Effects of inhaled fluticasone on bronchial hyperresponsiveness and airway inflammation in Mycoplasma pneumoniae-infected mice. Chest, 2003, 123(Suppl 3):427.
  • 6Chu HW, Campbell JA, Rino JG, et al. Inhaled fluticasone propionate reduoes concentration of Mycoplasma pneumoniae, inflammation, and bronchial hyperresponsiveness in lungs of mice. J Infect Dis, 2004, 189(6):1119-1127.
  • 7Matsuoka M, Narita M, Okazaki N, et al. Characterization and molecular analysis of macrolide-resistant Mycoplasma pneumoniae clinical isolates obtained in Japan. Antimicrob Agentas Chemother, 2004, 48(12):4624-4630.
  • 8张惠玉,田玲,岳爱红.儿童哮喘诊疗手册.北京:人民军医出版社,2013:147-149.
  • 9Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: evidence-based guidelines: American College of Chest Physicians/American College of Astama, Allergy,and Immunology. Chest, 2005, 127(1):335-371.
  • 10Principi N, Esposito S. Macrolide-resistant Mycoplasma pneumoniae : its role in respiratory infection J]. J Antimicrob Chemother,2013,68 ( 3 ) :506-511. DOI : 10.1093/jac/dks457.

共引文献184

同被引文献5

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部