尼莫地平治疗脑出血并破入脑室62例临床疗效观察

Clinical Observation of 62 Cases of Cerebral Hemorrhage Complicated with Ventricular Rupture Treated with Nimodipine

目的:探讨尼莫地平治疗脑出血并破入脑室62例临床疗效观察。方法:选取我院收治的脑出血患者62例,随机分为两组,对照组进行降颅压、止血及神经营养等常规治疗,研究组在对照组基础上应用尼莫地平治疗。结果:研究组治疗效果好于对照组(P<0.05);研究组不良反应发生率与对照组相比无明显差异(P>0.05);治疗前两组NIHSS评分对比无显著差异(p>0.05),治疗后两组上述评分均明显下降,其中研究组明显低于同期对照组,差异有统计学意义(P<0.05)。结论:脑出血并破入脑室的治疗过程当中,尼莫地平的治疗效果理想,安全性高。

Objective:To investigate the clinical efficacy of nimodipine in the treatment of 62 cases of cerebral hemorrhage with ventricular rupture.Methods:62 patients with cerebral hemorrhage admitted to our hospital randomly divided into two groups.The control group received routine treatment such as lowering intracranial pressure,hemostasis and neuronutrition,while the study group received nimodipine treatment on the basis of the control group.Results:The therapeutic effect of the study group was better than that of the control group(P<0.05);The incidence of adverse reactions in the study group was not significantly different from that of the control group(P>0.05);There was no significant difference in NIHSS score between the two groups before treatment(P>0.05);After treatment,the above scores of the two groups were significantly decreased,and the research group was significantly lower than that of the control group at the same time,the difference was significant.Statistical significance(P<0.05).Conclusion:Nimodipine is effective and safe in the treatment of intracerebral hemorrhage with ventricular rupture.