碘海醇在冠脉介入治疗中对肾功能的影响及相关护理

Effect of Iohexol on Renal Function in Coronary Intervention and Related Nursing Care

目的:分析碘海醇在冠脉介入治疗中对肾功能的影响及相关护理要点。方法:以本院冠脉接入治疗患者为研究对象,共选取56例,根据肾功能状况进行划分,即A组(肾功能正常组)、B组(肾功能轻度损害组),每组28例,将A组具体分为非水化组、水化组(均14例),B组分为非水化组、水化组(均14例),水化组进行0.9%的氯化钠注射液静脉注射,非水化组未进行静脉补液。对患者进行术前、术后观察,同时予以相应护理工作。结果:A组患者造影剂肾病发病率为3.5%,B组发病率为32.1%,对比差异存在统计学意义(P<0.05)。在水化组中,造影剂肾病的发病率7.1%,较低于非水化组28.5%,组间差异有统计学意义(P<0.05),有2例患者需要予以血液透析。在进行血尿素氮(BUN)与与血肌酐(Scr)的比较时,A组术前术后对比无意义(P<0.05)。B组术后指标较高于术前,且差异有意义(P<0.05);和水化组比较,非水化组指标显著提升(P<0.05)。结论:在冠脉介入治疗过程,碘海醇在肾功能损害患者中的治疗效果较为理想,选择合理水化、优化护理,是降低肾功能损伤的关键,可以避免发生造影剂肾病,提升患者临床疗效。

Objective:To analyze the effect of iohexol on renal function and related nursing points in coronary intervention therapy.Methods:56 patients with coronary artery access therapy in our hospital were selected and divided into two groups according to the status of renal function:group A(normal renal function group)and group B(mild impairment of renal function group).28 patients in each group were divided into non-hydration group and hydration group(all 14 cases).Group B was non-hydration group and hydration group(all 14 cases).The chemical group received intravenous injection of 0.9%sodium chloride injection,while the non-hydration group did not receive intravenous infusion.The patients were observed before and after operation,and the corresponding nursing work was given at the same time.Results:The incidence of contrast-induced nephropathy was 3.5%in group A and 32.1%in group B.There was significant difference between the two groups(P<0.05).In the hydration group,the incidence of contrast-induced nephropathy was 7.1%,which was lower than 28.5%in the non-hydration group.The difference between the two groups was significant(P<0.05).Two patients needed hemodialysis.There was no significant difference between BUN and Scr before and after operation in group A(P<0.05).Postoperative indicators in group B were higher than those before operation,and the difference was significant(P<0.05);compared with the hydration group,the indicators in non-hydration group increased significantly(P<0.05).Conclusion:In the process of coronary interventional therapy,iohexol has a better therapeutic effect in patients with renal impairment.Choosing reasonable hydration and optimizing nursing is the key to reduce renal impairment.It can avoid the occurrence of contrast-induced nephropathy and improve the clinical efficacy of patients.