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舒芬太尼分别复合地佐辛、酮咯酸氨丁三醇静脉自控镇痛对LC术后患者疼痛及镇静程度的影响观察

Effect of Patient-controlled Intravenous Analgesia with Sufentanil Combined with Dezocine or Ketorolac Tromethamine on Pain and Sedation of Patients after LC
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摘要 目的:探讨舒芬太尼分别复合地佐辛、酮咯酸氨丁三醇静脉自控镇痛对腹腔镜胆囊切除术(LC)术后患者疼痛及镇静程度的影响。方法:回顾性分析我院2018年1月至2019年10月期间行LC手术患者80例的临床资料,将应用舒芬太尼复合地佐辛静脉自控镇痛的40例患者的临床资料归为对照组,将应用舒芬太尼复合酮咯酸氨丁三醇静脉自控镇痛的40例患者的临床资料归为观察组,比较两组疼痛及镇静程度。结果:观察组术后4h、8h、12h、24h时视觉模拟评分法(VAS)评分、镇静评分量表(Ramsay)评分均低于对照组,差异有统计学意义(P<0.05)。结论:与舒芬太尼符合地佐辛静脉自控镇痛比较,LC手术患者术后应用舒芬太尼复合酮咯酸氨丁三醇静脉自控镇痛的效果较好,可以有效减轻患者术后疼痛,改善术后镇静效果。 Objective:To investigate the effect of patient-controlled intravenous analgesia(PCIA)with sufentanil combined with dezocine or ketorolac tromethamine on degree of pain and sedation of patients after laparoscopic cholecystectomy(LC).Methods:The clinical data of 80 patients with LC in the hospital from January 2018 to October 2019 were retrospectively analyzed.The clinical data of 40 patients with PCIA of sufentanil combined with dezocine were included in control group,and the clinical data of 40 patients with PCIA of sufentanil combined with ketorolac tromethamine were included in observation group.The degree of pain and sedation was compared between two groups.Results:After surgery for 4h,8h,12h and 24h,the scores of visual analogue scale(VAS)and Ramsay sedation scale in observation group were lower than those in control group(P<0.05).Conclusions:Compared with PCIA of sufentanil combined with dezocine,the application of PCIA of sufentanil combined with ketorolac tromethamine in patients after LC has better effects,it can effectively reduce postoperative pain and improve postoperative sedative effects.
作者 黄江焱 HUANG Jiang-yan(Affiliated Hospital of Jiujiang University,Jiujiang Jiangxi 332000,China)
出处 《药品评价》 CAS 2019年第23期11-12,共2页 Drug Evaluation
关键词 腹腔镜胆囊切除术 舒芬太尼 地佐辛 酮咯酸氨丁三醇 疼痛程度 镇静 Laparoscopic Cholecystectomy Sufentanil Dezocine Ketorolac Tromethamine Degree of Pain Sedation
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