地佐辛在无痛胃肠镜检查麻醉中的使用效果观察

Observation on Application Effects of Dezocine in the Anesthesia of Painless Gastroscopy Examination

目的:观察地佐辛在无痛胃肠镜检查麻醉中的使用效果。方法:选取于我院进行无痛胃肠镜检查的患者90例,随机分为对照组和观察组,45例/组。对照组使用芬太尼复合丙泊酚静脉麻醉,观察组使用地佐辛复合丙泊酚静脉麻醉,比较麻醉诱导前(T1)、插管时(T2)、术中(T3)、术毕30min(T4)等4个时间点两组平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO2)、呼吸频率(RR),统计两组苏醒时间、丙泊酚用量、不良反应发生率。结果:T2时观察组MAP低于对照组(P<0.05);T2、T3时观察组RR、SpO2高于对照组(P<0.05);观察组苏醒时间、丙泊酚用量均少于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05)。结论:地佐辛可以安全有效地应用于无痛胃肠镜检查麻醉。

Objective:To observe the application effects of dezocine in the anesthesia of painless gastroscopy examination.Methods:90 patients with underwent painless gastrointestinal endoscopy in our hospital were randomly divided into control group and observation group,45 cases/group.Control group was given fentanyl and propofolintravenous anesthesia,and observation group was given dezocine combined with propofol intravenous anesthesia.The mean arterial pressure(MAP),heart rate(HR),oxygen saturation(SpO2)and respiratory rate(RR)were compared between the two groups before anesthesia induction(T1),at intubation(T2),during surgery(T3)and at 30 min after surgery(T4).And the recovery time,propofol dosage and incidence rate of adverse reactions were counted in the two groups.Results:The MAP in observation group was lower than that in control group at T2(P<0.05).The RR and SpO2in observation group were higher than those in control group at T2 and T3(P<0.05).The recovery time and propofol dosage in observation group were less than those in control group(P<0.05).The incidence rate of adverse reactions in observation group was higher than that in control group(P<0.05).Conclusions:Dezocine can be safely and effectively applied in the anesthesia of painless gastroscopy examination.