23例行PGT妊娠患者与其产前诊断结果的一致性分析

Coherence analysis of 23 patients with PGT pregnancy and their prenatal diagnosis

目的初步探讨胚胎植入前遗传学检测结果的准确性。方法选取2017.6-2019.6在新疆佳音医院通过胚胎植入前遗传学检测妊娠,并选择在此进行羊水穿刺行产前诊断的23位患者,对他们的检测结果进行回顾性分析来验证胚胎植入前遗传学检测结果的准确性。结果 23位患者羊水核型分析结果为正常核型或携带者,羊水拷贝数分析结果显示均未见检测范围内的异常。结论胚胎植入前遗传学检测结果准确,可信度高。

Objective To investigate the accuracy of preimplantation genetic testing results. Methods From June 2017 to June2019, 23 patients who were performed by preimplantation genetic testing for pregnancy in Jiayin hospital of Xinjiang were selected for prenatal diagnosis by amniocentesis, and their results were analyzed retrospectively to verify the accuracy of preimplantation genetic testing results. Results The results of karyotype analysis about amniotic fluid in 23 patients were normal. The results of amniotic fluid copy number analysis showed that there was no abnormality within the detection range. Conclusion The results of preimplantation genetic test are accurate and reliable.