治疗急性下肢深静脉血栓形成的临床应用

Clinical Application of Acute Deep Venous Thrombosis of Lower Extremity

目的总结治疗急性下肢深静脉血栓形成的方法以及治疗效果。方法选择该院2017年6月-2019年6月收治的92例急性下肢深静脉血栓患者,采取随机法分组。对照组46例患者接受低分子肝素治疗,试验组46例患者接受低分子肝素+盐酸替罗非班治疗。对比对照组与试验组急性下肢深静脉血栓患者的治疗效果、安全性以及下肢肢围差情况。结果试验组急性下肢深静脉血栓患者治疗总有效率以及治疗后下肢肢围差明显优于对照组,差异有统计学意义(P<0.05)。另外,2组患者用药后安全性比较,差异无统计学意义(P>0.05)。结论低分子肝素、盐酸替罗非班联合治疗急性下肢深静脉血栓更具安全性、有效性价值。

Objective To summarize the methods and therapeutic effects of acute deep venous thrombosis of lower extremities. Methods From June 2017 to June 2019,92 patients with acute deep venous thrombosis of lower extremities were randomly divided into two groups. 46 patients in the control group were treated with low molecular weight heparin and 46 patients in the experimental group were treated with low molecular weight heparin plus tirofiban hydrochloride.The therapeutic effect, safety and limb circumference difference of patients with acute deep venous thrombosis of lower extremity were compared between the control group and the experimental group. Results The total effective rate and limb circumference difference of the experimental group were significantly better than those of the control group,the difference was statistically significant(P<0.05). In addition, the safety of the two groups after treatment was compared,,the difference was not statistically significant(P>0.05). Conclusion The combination of low molecular weight heparin and tirofiban hydrochloride is more safe and effective in the treatment of acute deep venous thrombosis of lower extremities.