133例非创伤性婴儿颅内出血的临床特征分析

Analysis of clinical features of 133 infants with non-traumatic intracranial hemorrhage

目的总结非创伤性婴儿颅内出血的临床特征。方法收集133例非创伤性颅内出血婴儿的相关资料,总结其临床特征,采用Logistic回归对出血部位数量与继发性脑梗死的关系进行分析。结果婴儿颅内出血的性别构成存在男性较女性多的特点;引起非创伤性婴儿颅内出血最常见的致病因素是晚发型维生素K缺乏症;部分颅内出血患儿会出现继发性脑梗死,颅内出血部位数量与继发性脑梗死发生率无关(P均>0.05)。结论婴儿非创伤性颅内出血男性多于女性,最常见致病因素是晚发型维生素K缺乏症,出血部位的数量与继发脑梗死无关。

Objective To summarize the clinical features of infants presenting with non-traumatic intracranial hemorrhage intracranial hemorrhage.Methods Clinical data of 133 infants with intracranial hemorrhage were collected and the clinical features were analyzed.The relationship between quantity of hemorrhage sites and secondary cerebral infarction were statistically analyzed by logistic regression.Results The proportion of male infants with intracranial hemorrhage was higher than that of female counterparts.Late-onset vitamin K deficiency was the primary pathogenic cause of 133 infants.Partial infants presented with secondary cerebral infarction.The number of hemorrhage sites was not significantly correlated with the incidence rate of secondary cerebral infarction(both P>0.05).Conclusions The percentage of male infants with non-traumatic intracranial hemorrhage intracranial hemorrhage in infants is higher than that of female counterparts.Late-onset vitamin K deficiency is the primary cause of non-traumatic intracranial hemorrhage.The number of hemorrhage sites isn’t correlated with secondary cerebral infarction.