视网膜色素变性的中医综合治疗及用药规律分析

Comprehensive Treatment of Retinitis Pigmentosa in Traditional Chinese Medicine and Analysis of Medication Rules

目的回顾整理802例视网膜色素变性患者的中医治疗效果及用药规律。方法对802份视网膜色素变性患者病历资料收集整理,对视力、视野的疗效进行评价并分析其用药规律。结果802例视网膜色素变性患者中,视力显效280例,有效355例,无效167例,总有效率为79.18%;视野显效245例,有效315例,无效242例,总有效率为69.83%。常用中药为熟地黄、当归、生地黄、枸杞、黄芪、山药、山茱萸、党参、石斛、石决明、丹参、白术、桑葚、黄精、夜明砂、牛膝、柴胡、地龙、决明子、桃仁、红花、白芍、丹皮等。3个证型中均运用了当归、夜明砂、桃仁、红花、丹参、石决明这6味中药。结论视网膜色素变性常用的药对主要为补阴药+活血药、补气药+活血药、活血药+活血药。中医综合治疗有助于改善视网膜色素变性患者中医证候,提高视力、扩大视野,具有显著的临床疗效。

Objective To retrospectively review the traditional Chinese medicine treatment effects and medication rules in the treatment of 802 cases of patient with retinitis pigmentosa.Methods The medical records of 802 patients with retinitis pigmentosa were collected,and the effects of visual acuity and visual field were evaluated,and its medication rules were analyzed.Results Among 802 patients with retinal pigment degeneration,for visual acuity,there were 280 markedly effective cases,355 effective cases,and 167 ineffective cases,with total effective rate of 79.18%;for visual field,there were 245 markedly effective cases,315 effective cases,and 242 ineffective cases,with total effective rate of 69.83%.The commonly used Chinese herbs were Radix Rehmanniae Preparata,Radix Angelicae Sinensis,Radix Rehmanniae Recens,Fructus Lycii,Radix Astragali seu Hedysari,Rhizoma Dioscoreae,Fructus Corni,Radix Codonopsis,Herba Dendrobii,Concha Haliotidis,Radix Salviae Miltiorrhizae,Rhizoma Atractylodis Macrocephalae,Morus Alba,Rhizoma Polygonati,Feaces Vespertilio,Radix Achyranthis Bidentatae,Radix Bupleuri,Lumbricus,Semen Cassiae,Semen Persicae,Flos Carthami,Radix Paeoniae Alba,Cortex Moutan Radicis,etc.The 6 Chinese herbs of Radix Angelicae Sinensis,Feaces Vespertilio,Semen Persicae,Flos Carthami,Radix Salviae Miltiorrhizae,Concha Haliotidis were used in the 3 syndromes.Conclusion The common drug-pair in the treatment of retinitis pigmentosa are tonifying Yin herbs+activating blood circulation herbs,tonifying Qi herbs+activating blood circulation herbs,activating blood circulation herbs+activating blood circulation herbs.The comprehensive treatment of traditional Chinese medicine is helpful to improve the syndromes of traditional Chinese medicine in patients with retinal pigment degeneration,improve vision,expand the visual field,and has significant clinical effects.