小儿呼吸系统感染病原菌的耐药性分析

Analysis of drug resistance of pathogenic bacteria in respiratory system infection of children

目的:探究小儿呼吸系统感染病原菌的耐药性,为科学使用抗菌类药物提供参考。方法:2017年5月-2018年5月收治小儿呼吸系统疾病患者240例,共760份痰液样本,分析检测结果。结果:760份痰液样本中,检出病原菌255株。在耐药性方面,铜绿假单胞菌对复方磺胺甲噁唑片以及氨苄西林的耐药性较高,大肠埃希菌和肺炎克雷伯菌对酰胺类抗生素药物的抗药性较高,噬麦芽窄食单胞菌对于碳青霉烯类药物的耐药性较高等。结论:小儿呼吸系统感染常见病原菌对β-内酰胺类的抗生素具有较高耐药性,在临床用药时,需要在检测之后,按照药敏结果以及病原菌谱合理使用药物。

Objective:To explore the drug resistance of pathogenic bacteria in children's respiratory system infection and provide reference for scientific use of antibiotics.Methods:From May 2017 to May 2018,240 children with respiratory diseases were selected,with a total of 760 sputum samples,we analyzed the test results.Results:In 760 sputum samples,255 pathogenic bacteria were detected.In terms of drug resistance,Pseudomonas aeruginosa had high resistance to sulfamethoxazole and ampicillin,Escherichia coli and Klebsiella pneumoniae were highly resistant to amide antibiotics,The resistance of Stenotrophomonas maltophilia to carbapenems was high.Conclusion:The common pathogens of respiratory system infection in children are highly resistant toβ-lactam antibiotics,in the clinical use of drugs,it is necessary to use the drugs reasonably according to the drug sensitivity results and the general pathogenic bacteria after testing.