泌尿系感染患者病原菌分布及耐药性分析

Distribution and drug resistance of pathogens in patients with urinary tract infection

目的:分析泌尿系感染患者病原菌分布情况及耐药性。方法:2017年1月-2018年12月收集门诊及住院患者尿液标本分离培养获得病原菌9252份,进行细菌鉴定及药敏试验。结果:尿培养标本9252份,检出病原菌1688株,检出率为18.2%;其中革兰阴性菌1285株(76.1%),革兰阳性菌322株(19.1%),真菌81株(4.8%);检出率最高的前5位病原菌依次为大肠埃希菌、肺炎克雷伯菌、粪肠球菌、表皮葡萄球菌、奇异变形杆菌。结论:泌尿系感染病原菌以革兰阴性菌为主,大肠埃希菌是主要病原菌,随多重耐药种类和数量不断增加,临床医生应根据药敏结果,正确合理使用抗菌药物,提高临床抗感染治疗的效果。

Objective:To explore the distribution and drug resistance of pathogens in patients with urinary tract infection.Methods:From January 2017 to December 2018,urine samples of outpatients and inpatients were selected and 9252 pathogenic bacteria were isolated and cultured,bacteria identification and drug sensitivity test were carried out.Results:In 9252 urine culture samples,1688 pathogenic bacteria were detected,the detection rate was 18.2%.Among them,1285(76.1%)were Gram-negative bacteria,322(19.1%)were Gram-positive bacteria,81(4.8%)were fungi.The top five pathogens with the highest detection rate were Escherichia coli,Klebsiella pneumoniae,Enterococcus faecalis,Staphylococcus epidermidis and Proteus mirabilis.Conclusion:Gram negative bacteria are the main pathogens of urinary tract infection,and Escherichia coli is the main pathogen,with the increase of the types and quantity of multidrug resistance,clinicians should use antibiotics correctly and reasonably according to the results of drug sensitivity,so as to improve the effect of clinical anti infection treatment.