磁敏感血管征在急性脑梗死诊疗中的临床应用

Clinical Application of Susceptibility Vessel Sign in Diagnosis and Treatment of Acute Cerebral Infarction

磁敏感加权成像(SWI)是近年来逐渐发展并应用于临床的一项新的磁共振序列,SWI主要利用组织之间磁敏感性的不同形成图像对比。血红蛋白的代谢产物为体内常见的磁敏感物质,在急性脑梗死中,责任动脉内的血栓中含有大量的脱氧血红蛋白,而脱氧血红蛋白作为顺磁性物质可在SWI中表现为直径超过对侧血管的低信号影,这一影像学征象被称为磁敏感血管征(SVS)。SVS除了可用于对急性脑梗死责任动脉内血栓的诊断外,还可进一步分析卒中亚型,评估病情严重程度及临床预后,从而对急性脑梗死治疗方案的选择提供相关的参考信息。

Magnetic susceptibility weighted imaging(SWI)has been developing increasingly in recent years,as a new magnetic resonance sequence.SWI forms a new source of contrast in magnetic resonance,because of the magnetic susceptibility differences of various compounds.The metabolites of hemoglobin are common magnetic susceptible substances in body.In acute cerebral infarction,the thrombus in the responsible artery contains a large amount of deoxyhemoglobin.As a paramagnetic substance,deoxyhemoglobin can present in SWI as a low-signal image with a diameter larger than that of the contralateral vessels,and this imaging sign is called susceptibility vessel sign(SVS).SVS can be used to detect intra-arterial thrombus in acute cerebral infarction.Besides,SVS may also be associated with stroke subtype,extent of infarct and prognosis,so as to provide some reference information for the treatment of cerebral infarction.