急性冠脉综合征危险评分的研究进展

Risk Scores of Acute Coronary Syndrome

急性冠脉综合征是冠心病的一种严重类型,其预后不良,严重影响患者的生活质量及寿命。探索并推广有效的急性冠脉综合征风险划分和预后预测方法不仅有利于临床诊疗决策的制定,且对冠心病临床研究的设计与实施起到重要作用。为比较不同急性冠脉综合征预后预测评分,探寻符合当代情况,且适用于真实世界的风险划分和预后评估系统,作者回顾并讨论了GRACE、TIMI、PURSUIT、CADILLAC、Zwolle等危险评分的特点及研究进展。最后,从不同角度阐述危险评分的应用和发展前景,以期达到指导评分系统研究的目的。

Acute coronary syndrome is a severe type of coronary heart disease,which is associated with poor prognosis,and affects the quality of life of patients seriously.Promoting effective methods to predict the prognosis and assessing the risk of acute coronary syndrome is beneficial to make clinical diagnosis and treatment decisions.Also,it can improve the quality of design and implementation of clinical research.In order to compare different predictive risk scores of prognosis and search for the predictive system which is applicable for the real world,we review the characteristics and progresses of GRACE,TIMI,PURSUIT,CADILLAC and Zwolle risk scores.Finally,we elucidate the application and developing prospects of risk scores from different perspectives,which may instruct the research of risk scores.