太极拳对奥氮平致体重增加精神分裂症患者的作用

The effect of Taijiquan on weight gain in schizophrenic patients caused by olanzapine

目的:探讨太极拳对奥氮平致体重增加精神分裂症患者的作用。方法:2018年1月-2018年10月收治精神分裂症患者80例,随机分为两组各40例。两组均服用奥氮平片治疗,研究组合并2次/d的太极拳习练。治疗8周后,比较两组患者各项指标水平。结果:研究组治疗前后体重、体重指数(BMI)、空腹血糖(GLU)、甘油三酯(TG)、总胆固醇(TC)比较,差异无统计学意义(P>0.05);对照组治疗后体重、BMI、GLU、TG、TC较治疗前明显增加,差异有统计学意义(P<0.05)。结论:辅以太极拳习练能改善奥氮平治疗精神分裂症引起的糖脂代谢紊乱,有效防止体重增加,从而提高患者服药依从性。

Objective:To explore the effect of Taijiquan on weight gain in schizophrenic patients caused by olanzapine.Methods:From January 2018 to October 2018,80 schizophrenics were selected and randomly divided into two groups of 40 cases in each.Both groups were treated with olanzapine tablets,and the study group received 2 times of Taijiquan practice per day.After 8 weeks of treatment,we compared the levels of the two groups.Results:In the study group,there was no significant difference in body weight,body mass index,fasting blood glucose,triglyceride and total cholesterol before and after treatment(P>0.05).In the control group,after treatment,the body weight,body mass index,fasting blood glucose content,triglyceride value and total cholesterol value increased significantly compared with before treatment,the difference was statistically significant(P<0.05).Conclusion:Taijiquan practice can improve the disorder of glucose and lipid metabolism caused by olanzapine in the treatment of schizophrenia,effectively prevent weight gain,so as to improve the compliance of patients with medication.