卡培他滨治疗晚期结直肠癌现状及研究进展

Current situation and research progress of capecitabine in the treatment of advanced colorectal cancer

化疗是晚期结直肠癌患者的主要治疗手段,作为新一代口服氟尿嘧啶类药物,卡培他滨因高效、安全和便利等优点已成为晚期结直肠癌患者治疗的最基本药物。随着分子靶向药物及免疫治疗的加入,进一步改善了晚期转移性患者的生存周期。由于患者的个体差异,化疗方案的具体选择应根据患者情况而定。文章对卡培他滨治疗晚期结直肠癌患者的现状及进展进行综述,以指导化疗方案的选择。

Chemotherapy is the main treatment for advanced colorectal cancer.As a new generation of oral fluorouracil drugs,capecitabine has become the most basic drug for the treatment of advanced colorectal cancer due to its advantages of high efficiency,safety and convenience.With the addition of molecular targeted drugs and immunotherapy,the survival cycle of patients with advanced metastasis has been further improved.Due to the individual differences of patients,the specific choice of chemotherapy should be based on the situation of patients.This article reviews the current situation and progress of capecitabine in the treatment of advanced colorectal cancer,in order to guide the choice of chemotherapy.