摘要
支气管肺发育不良(bronchopulmonary dysplasia,BPD)是早产儿最严重的肺部疾病之一,也是早产儿死亡的重要原因. BPD的病理生理学机制尚不清楚,对于该疾病预防性及针对性的治疗策略也十分有限,但目前已经在血液、肺泡灌洗液、呼出气体冷凝物、尿液等体液中发现多种生物标记物用于早期识别BPD的高风险患儿,以及预测该疾病的严重程度及预后.
Bronchopulmonary dysplasia(BPD)is one of the most serious lung diseases in premature infants and an important cause of death in preterm infants.The pathophysiological mechanism of BPD is still unclear.The preventive and targeted treatment strategies for this disease are also very limited.However,various biomarkers have been found in blood,alveolar lavage fluid,exhaled gas condensate,and urine.It is used to identify high-risk children with BPD early and to predict the severity and prognosis of the disease.
作者
潘雨晴(综述)
富建华(审校)
Pan Yuqing;Fu Jianhua(Neonatal Department,Shengjing Hospital of China Medical University,Shenyang 110004,China)
出处
《中国小儿急救医学》
CAS
2019年第12期932-936,共5页
Chinese Pediatric Emergency Medicine
基金
国家自然科学基金(81571479)。
