5326例胃镜检查前患者血液传染病四项检测结果分析

Analysis and significance of the detection of the first four infectious diseases in 5326 patients with gastroscopy

目的通过对5 326例胃镜检查前患者血清中四项传染病检测结果分析,探讨四项传染病检测的重要性,以便加强医疗安全,预防交叉感染,减少微创诊疗引起的医患纠纷。方法用金标法对5 326例胃镜检查前患者血清中乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、梅毒螺旋体抗体(抗-TP)、人类免疫缺陷病毒抗体(抗-HIV)进行初筛检测分析,阳性标本用酶联免疫吸附试验法进一步复查。结果 5 326例受检者四项传染病检测中HBsAg阳性630例,占11.83%,抗-HCV阳性89例,占1.67%,抗-TP阳性61例,占1.15%,12例抗-HIV初筛阳性者经市疾病控制中心确认有9例为阳性,占0.17%。HBsAg与抗-HCV同时阳性5例,抗-HCV与抗-TP同时阳性2例,抗-HCV与抗-HIV同时阳性1例。结论对患者胃镜检查前进行传染病检测不但可以及时了解患者的感染情况,而且可以有效预防和避免因黏膜破损引起的医疗纠纷,同时在检查过程中加强医护人员的自我保护,减少医院感染,降低职业暴露的危险,对保护医患双方具有十分重要的临床意义。

Objective By analyzing the results of four infectious diseases in the serum of 5 326 patients before gastroscope examination, the importance of four infectious diseases testing was discussed in order to strengthen medical security, prevent cross-infection, and reduce the disputes between doctors and patients caused by minimally invasive diagnosis and treatment. Methods The screening of HBsAg, HCV antibody(anti-HCV), helicosome antibody(anti-TP) and human immunodeficiency virus antibody(anti-HIV) in the serum of 5 326 patients prior to gastroscopy was performed by gold standard method. The positive specimen was further reviewed by enzyme-linked immunoadsorption test. Results The total positive rate of the four infectious diseases tested in 5 326 and the HBsAg positive was 630, accounting for11.83 %, the anti-HCV positive was 89, accounting for 1.67 %, and the anti-TP positive was 61, accounting for 1.15 %.Twelve cases of positive initial screening for anti-HIV were confirmed by the City Centers for Disease Control as positive in 9 cases, accounting for 0.17 %. HBsAg and anti-HCV were positive in 5 cases, Two cases of anti-HCV and antiTP were positive at the same time, Anti-HCV and anti-HIV positive 1 case. Conclusion The examination of infectious diseases before the gastroscope examination of patients can not only understand the infection situation of patients in a timely manner, but also effectively prevent and avoid medical disputes caused by mucosa damage, and at the same time strengthen the self-protection of medical personnel and reduce hospital infections during the inspection process. Reducing the risk of occupational exposure is of great clinical significance to the protection of both doctors and patients.Key.