植入型心律转复除颤器在心肌梗死后心脏性猝死中的研究进展

Implantable Cardioverter Defibrillator in Sudden Cardiac Death after Myocardial Infarction

心脏性猝死(SCD)是由各种心脏因素引起的意外死亡,通常发生在症状出现后1 h内。冠心病和急性心肌梗死是SCD的主要病因。植入型心律转复除颤器是预防SCD最有效的措施,有效提高了心肌梗死后SCD高危患者的生存率,成为SCD一级预防的标准治疗方法。近年来,在临床上的应用有了新进展。现综述SCD的流行病学、心肌梗死后SCD的发生机制和心律转复除颤器在心肌梗死后SCD中的应用进展。

Sudden cardiac death is an unintentional death caused by a variety of cardiac factors,usually within one hour of the onset of symptoms. Coronary heart disease and acute myocardial infarction are the main causes of sudden cardiac death. Implantable cardioverter defibrillator is the most effective measure to prevent SCD,which can effectively improve the survival rate of high-risk patients with SCD after myocardial infarction and become the standard treatment for primary prevention of SCD. In recent years,new progress has been made in the clinical application. This article reviews the epidemiology of SCD,occurrence mechanism of SCD after myocardial infarction and application of implantable cardioverter defibrillator in SCD after myocardial infarction.