脂蛋白相关磷脂酶A2与冠心病的相关性研究进展

Lipoprotein-associated Phospholipase A2 and Coronary Heart Disease

目前中国居民冠心病的发病率和死亡率逐年增高。研究发现动脉粥样硬化是一个血管炎症反应的过程,传统的血清炎性标志物与冠心病的相关性缺乏特异性。新型血清炎性标志物血浆脂蛋白相关磷脂酶A2与冠心病的相关性尚未得到证实。现就脂蛋白相关磷脂酶A2与冠心病的相关性研究进展做一综述。

At present,the morbidity and mortality of coronary heart disease in Chinese residents have increased year by year. Studies have found that atherosclerosis is a process of vascular inflammatory response,and the association between traditional serum inflammatory markers and coronary heart disease is lacking in specificity. The correlation of the novel serum inflammatory marker plasma lipoproteinassociated phospholipase A2 with coronary heart disease has not been confirmed. This article reviews the research progress of the relationship between lipoprotein-associated phospholipase A2 and coronary heart disease.