低分子肝素钙联合硫酸镁对早发型重度子痫前期患者的疗效被引量：6

下载PDF

导出

摘要目的观察低分子肝素钙联合硫酸镁对早发型重度子痫前期患者的疗效。方法选取河南科技大学附属许昌市中心医院2015年1月至2018年12月收治的200例早发型重度子痫前期患者,根据治疗方案分为两组,每组100例。常规组接受硫酸镁治疗,干预组接受低分子肝素钙联合硫酸镁治疗。比较两组治疗前、治疗7 d后血压、凝血四项及妊娠结局。结果治疗7 d后,干预组收缩压、舒张压、血浆FIB水平均低于常规组,APTT、TT、PT均长于常规组,差异有统计学意义(均P<0.05)。干预组不良妊娠结局出现率[17.00%(17/100)]低于常规组[35.00%(35/100)],差异有统计学意义(P<0.05)。结论低分子肝素钙联合硫酸镁可有效降低早发型重度子痫前期患者血压,改善患者凝血功能,减少不良妊娠结局的出现。

作者常璐

机构地区河南科技大学附属许昌市中心医院产科

出处《河南医学研究》 CAS 2020年第5期881-883,共3页 Henan Medical Research

关键词子痫前期硫酸镁低分子肝素钙血压凝血妊娠结局

分类号 R714 [医药卫生—妇产科学]

引文网络
相关文献

参考文献4

1王露姿.硫酸镁联合低分子肝素钠对重度子痫前期患者血压控制及母婴结局的影响[J].国际医药卫生导报,2017,23(20):3239-3241. 被引量：12
2丁丹妮,贺鑫,杨伟辉.小剂量硫酸镁联合低分子肝素治疗对早发型重度子痫前期患者血压、24 h尿蛋白及母婴并发症的影响[J].中国妇幼保健,2018,33(9):1988-1990. 被引量：43
3毛小刚,江红,刘韵,兰艳丽,权效珍,周敏,邢辉.低分子肝素钙对妊娠子痫患者肾功能、凝血功能及血压的影响[J].疑难病杂志,2016,15(5):494-497. 被引量：31
4无,孙宁玲.妊娠期高血压疾病血压管理中国专家共识[J].中华高血压杂志,2012,20(11):1023-1027. 被引量：132

二级参考文献53

1Peters RM, Flack JM. Hypertensive disorders of pregnancy[J]. J Obstet Gynecol Neonatal Nurs, 2004,33 (2) : 209-220.
2Duley L. The global impact of pre-eclampsia and eclampsia[J]. Semin Perinatol, 2009,33 (3) : 130-137.
3Bujold E, Roberge S, Lacasse Y, et al. Prevention of preeclamp- sia and intrauterine growth restriction with aspirin started in early pregnancy[J]. Obstet Gynecol, 2010,116 (2 Pt 1) : 402-414.
4Duley L. Pre-eclampsia, eclampsia, and hypertension[J]. Clin Evid (Online), 2011, pii : 1402.
5Magee LA, Helewa M, Moutquin JM, et al. Diagnosis,evalua- tion, and management of the hypertensive disorders of pregnancy [J]. J Obstet Gynaecol Can,2008,30(3 Suppl) :S1-48.
6American college of obstetricians and gynecologists. ACOG prac- tice bulletin No. 125: chronic hypertension in pregnancy[J]. Obstet Gynecol,2012,119(2 Pt 1) :396-407.
7American college of obstetricians and gynecologists. ACOG prac- tice bulletin No. 29:chronic hypertension in pregnancy[J]. Obstet Gynecol, 2001,98(1) : 177-185.
8ACOG committee on obstetric practice. ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Num- ber 33, January 2002. American college of obstetricians and gynecologists[J]. Int J Gynaecol Obstet, 2002,77 (1) : 67-75.
9Irgens HU, Reisaeter L, Irgens LM, et al. Long term mortality of mothers and fathers after pre-eclampsia: population based co- hort study[J]. BMJ,2001,323(7323) : 1213-1217.
10Wilson BJ, Watson MS, Prescott GJ, et al. Hypertensive disea- ses of pregnancy and risk of hypertension and stroke in later life: results from cohort study[J]. BMJ,2003,326(7394):845.