额区尖波与小儿热性惊厥的相关性研究

The correlation between Frontal sharp and febrile seizures in children

目的:探讨额区尖波与小儿热性惊厥(FS)的关系。方法:收集2014年4月至2018年4月在潍坊医学院附属医院电生理室检査的FS患儿94例,同时将健康查体儿童94例设置为对照组。188例受试者均行动态脑电图检査,FS组中70例患儿行颅脑核磁共振成像(MRI)检査,应用SPSS 19.0统计软件统计分析,计数资料组间比较采用才检验。结果:①在FS组,脑电图有额区尖波者70例,其他异常者6例(脑电图表现为广泛性或其他局灶性放电),无尖波者18例,健康儿童组脑电图有额区尖波者32例,两组比较差异有统计学意义(P<0.05);②FS组脑MRI检查,有髓鞘化者38例,无髓鞘化者32例,38例髓鞘化患儿中有尖波者20例,无尖波者18例。结论:伴有额区尖波的儿童容易岀现FS,伴有额区尖波的FS患儿与MRI髓鞘化表现无相关性。

Objective:To explore the relationship between frontal physiological sharp and febrile seizures(FS).Methods:A total of 94 patients with febrile seizures were enrolled from April 2014 to April 2018 in affiliated hospital of Weifang medical university.In addition,94 health children were enrolled as control group.All participants received ambulatory electroencephalogram.All of the 70 patients with febrile seizures underwent MRI examination.Statistical software spssl9.0 was used to analyze the data between groups.Results:①In FS group,there were 70 cases with frontal sharp wave,6 cases with other abnormalities(EEG showed extensive or other local discharge),18 cases without sharp wave,and 32 cases with frontal sharp wave in healthy children group.There was statistically significant difference between the two groups(P<0.05).②In the febrile convulsion group,38 cases had myelination,32 cases had no myelination,20 cases had sharp wave,18 cases had no sharp wave.Conclusion:Children with frontal sharp wave are prone to febrile convulsion.There was no correlation between MRI myelination and febrile convulsion with frontal sharp wave.