凝血酶联合奥美拉唑治疗胃出血的疗效及安全性观察

Efficacy and Safety of Thrombin Combined with Omeprazole in the Treatment of Gastrorrhagia

目的:分析讨论在胃出血中采用凝血酶和奥美拉唑治疗的具体效果和实际价值。方法:选取某院2017年1月~2018年12月胃出血患者96例,根据入院先后将其均分为两组,每组48例。对照组使用凝血酶治疗;观察组使用凝血酶+奥美拉唑治疗,比较两组患者总有效率和不良反应发生率。结果:与对照组总有效率(72.91%)相比,观察组总有效率(95.83%)明显较高,差异具有统计学意义(P<0.05);与对照组不良反应发生率(29.17%)相比,观察组不良反应发生率(12.50%)明显较低,差异具有统计学意义(P<0.05)。结论:在胃出血中采用凝血酶和奥美拉唑治疗整体效果较好,不良反应发生率较低,在临床治疗中可进行推广应用。

Objective:To analyze the specific effects and practical value of thrombin combined with omeprazole in the treatment of gastrorrhagia.Methods:96 patients with gastrorrhagia from January 2017 to December 1818 were enrolled.According to the admission,they were divided into two groups,48 in each group.Group 1 was the control group and treated with thrombin.The group 2 were the observation group and treated with thrombin+omeprazole.The total effective rate and incidence of adverse reactions were compared between the two groups.Results:Compared with the total effective rate of the control group(72.91%),the total effective rate of the observation group(95.83%)was significantly higher,and the difference was statistically significant(P<0.05).Compared with the incidence of adverse reactions in the control group(29.17%),the incidence of adverse reactions in the observation group(12.50%)was significantly lower,and the difference was statistically significant(P<0.05).Conclusion:The use of thrombin and omeprazole in the treatment of gastric hemorrhage has a better overall effect,and the incidence of adverse reactions is low.It can be popularized and applied in clinical treatment.