哮喘患儿潮气呼吸肺功能测定参数的临床评估价值及其与临床症状评分的关系研究

Clinical evaluation value of measurement parameters of tidal breathing pulmonary function in children with asthma and their relationship with clinical symptoms scores

目的探究哮喘患儿潮气呼吸肺功能测定参数的临床评估价值及其与临床症状评分的关系。方法选取2017年1月至2019年1月于我院接受治疗的122例哮喘患儿为观察组,并选取同期进行体检的健康儿童86例为对照组,给予两组同样的潮气呼吸肺功能测定,比较两组对象肺功能指标变化,并记录观察组患儿临床症状评分结果,分析哮喘患儿肺功能指标与临床症状评分的相关性。结果122例哮喘患儿中,轻度哮喘31例,中度哮喘76例,重度哮喘15例;轻度哮喘患儿、中度哮喘患儿、重度哮喘患儿及健康对照组之间的达峰时间比(TPTEF/TE)、每千克潮气量、呼吸频率、吸呼比、达峰容积比(VPEF/VE)、潮气呼吸峰流速,25%、50%、75%潮气量时呼吸流速比较均有统计学意义(P<0.05);哮喘患儿TPTEF/TE及VPEF/VE指标水平与临床症状评分呈负相关(P<0.05)。结论哮喘患儿肺功能测定参数与临床症状轻重程度具有一定相关性,其可作为评估病情严重程度的指标之一。

Objective To investigate the clinical evaluation value of measurement parameters of tidal breathing pulmonary function in children with asthma and their relationship with clinical symptoms scores.Methods A total of 122 children with asthma who were treated in our hospital from January 2017 to January 2019 were enrolled in observation group.Another 86 healthy children who underwent physical examination at the same time were selected as control group.The two groups were given the same measurement of tidal breathing pulmonary function.The changes of pulmonary function indexes were compared between the two groups,and the clinical symptoms scores were recorded in observation group.The correlation between pulmonary function indexes and clinical symptoms scores was analyzed among the children with asthma.Results Among the 122 children with asthma,there were 31 cases of mild asthma,76 cases of moderate asthma and 15 cases of severe asthma.There were statistically significant differences in the TPTEF/TE,VT/kg,Rr,Ti/Te,VPEF/VE,PEF,TEF25%,TEF50%and TEF75%among the children with mild asthma,children with moderate asthma,children with severe asthma and healthy control group(all P<0.05).The TPTEF/TE and VPEF/VE in children with asthma were negatively correlated with clinical symptoms scores(P<0.05).Conclusion The measurement parameters of pulmonary function in children with asthma have a certain correlation with the severity of clinical symptoms,which can be used as one of the indicators to assess the severity of the disease.