感音神经性聋成人不同刺激声ASSR反应阈与纯音听阈的相关性分析

Correlation of ASSR Evoked and Pure Tone Hearing Thresholds of Different Stimuli in Adults with Sensorineural Hearing Loss

目的探讨调制声听性稳态反应(ASSR)、 CE-Chirp ASSR用于评估感音神经性聋成人客观听力的价值。方法对78例(131耳)感音神经性聋成人同时进行纯音听阈和调制声ASSR、 CE-Chirp ASSR测试,比较0.5~4 kHz各频率纯音听阈与调制声ASSR、CE-Chirp ASSR反应阈的相关性及差值。结果 0.5、1、2、4 kHz CE-Chirp ASSR反应阈与纯音听阈的相关系数(分别为0.77、0.73、0.80、0.88)均高于调制声ASSR反应阈与纯音听阈的相关系数(分别为0.64、0.61、0.78、0.84),调制声ASSR、CE-Chirp ASSR反应阈与纯音听阈均具有显著相关性(圴为P<0.01);0.5~4 kHz CE-Chirp ASSR反应阈和纯音听阈的差值(分别为8.09±4.74、10.76±5.86、7.44±7.95、6.11±9.14 dB)均明显小于调制声ASSR反应阈和纯音听阈间的差值(分别为14.31±6.38、13.85±6.25、17.17±6.29、13.58±4.35 dB),差异均有统计学意义(均为P<0.05)。结论 CE-Chirp ASSR快捷可靠,较调制声ASSR能更好地评估感音神经性聋成人的听力。

Objective To evaluate the values of different stimuli ASSR in objective hearing threshold assessment in comparison with traditional ASSR and CE-Chirp ASSR evoked and pure tone hearing thresholds.Methods Seventy-eight(131 ears) adults with sensorineural hearing loss were received pure tone threshold tests and traditional ASSR, and CE-Chirp ASSR tests. The pure tone hearing thresholds were compared with the ASSR, CE-Chirp ASSR thresholds for a correlation study.Results The traditional ASSR and CE-Chirp ASSR had significant correlation with the pure tone thresholds. The correlation coefficient between CE-Chirp ASSR and pure tone thresholds was slightly higher than that of traditional ASSR at 500 Hz, 1 000 Hz,2 000 Hz and 4 000 Hz.The mean values of absolute differences between CE-Chirp ASSR-induced and pure-tone hearing thresholds were significantly lower than the traditional ASSR-induced thresholds at 500 Hz,1 000 Hz,2 000 Hz,and 4 000 Hz,and the difference was statistically significant(P<0.05).Conclusion CE-Chirp ASSR is fast, reliable, and better than modulated traditional ASSR in assessing hearing in adults with sensorineural hearing loss.