乳酸杆菌与肝病研究进展

Progress on Lactobacillus and liver diseases

近年来肠道微生态与多种肝病的发生、发展受到越来越多的关注。益生菌因具有改善肠道屏障、激活免疫功能等多种有利于人体的功能而日益受到重视。乳酸杆菌作为主要的益生菌之一,与多种肝脏疾病的发生、发展和预后相关,尤其在酒精性脂肪肝及非酒精性脂肪肝治疗中作用的研究日益增多。不同乳酸杆菌与不同肝病的关系亦不尽相同,为临床应用乳酸杆菌调节肠道菌群及治疗肝病提供参考,本文就乳酸杆菌与肝病相关性及在肝病治疗中的应用作一综述。

In recent years,more and more attention has been paid to the relationship between intestinal microecology and the occurrence and development of various liver diseases.Probiotics are getting more and more attention due to their beneficial functions such as improving intestinal barrier and activating immune function.Lactobacillus,as one of the main probiotics,is associated with the occurrence,development and prognosis of various liver diseases,especially in the treatment of alcoholic fatty liver disease and nonalcoholic fatty liver disease.In order to provide reference for the clinical application of Lactobacillus in the regulation of intestinal flora in the treatment of liver diseases,this paper reviews the correlation between Lactobacillus and liver diseases and its application in the treatment of liver diseases.