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假基因在消化系统肿瘤中的研究进展 被引量:1

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摘要 长链非编码RNA(lncRNA)在肿瘤细胞的增殖、侵袭、转移和凋亡过程中发挥重要作用。假基因属于lncRNA家族的一员,具有与同源编码基因相似的序列,由于基因突变等原因丧失了原有的功能。现有研究已证实假基因可从表观遗传、转录及转录后水平调控相关基因的表达,进而影响肿瘤的增殖、转移和侵袭。本文就假基因的分类、作用机制及其与消化系统肿瘤的关系作一综述。
出处 《癌症进展》 2020年第3期217-219,244,共4页 Oncology Progress
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