成年男性睾丸微石症的生精功能分析

Spermatogenesis of testicular microlithiasis in adult males

目的探究睾丸微石症(testicular microlithiasis,TM)对成年男性精子质量的影响。方法回顾性分析2013年1月至2017年6月于淄博市中心医院门诊健康体检时发现的90例睾丸微石症患者为研究对象,按照超声检查的结果将其分为经典型睾丸微石症组(classic testicular microlithiasis,CTM组)50例和限制型睾丸微石症组(limited testicular microlithiasis,LTM组)40例;同时,随机选取同期常规健康查体的50例非睾丸微石症成年男性作为对照组。采集三组成员的精液,观察其精液质量的差异。结果三组成员睾丸阻力指数差异无统计学意义(P>0.05)。CTM组、LTM组和对照组睾丸动脉收缩峰值血流速度(peak of systolic velocity,PSV)差异具有统计学意义(P<0.05)。三组成员精子体积和畸形率差异无统计学意义(P>0.05)。与对照组成员比较,CTM组与LTM组成员精子质量总体下降。此外,CTM组与LTM组成员在精子密度、精子活力、PR、NP、IM等方面差异均具有统计学意义(均P<0.05)。结论睾丸微石症可以影响成年男性精子质量,CTM组精子质量明显低于LTM组。

Objective To explore the effect of testicular microlithiasis(TM) on the sperm quality in adult males. Methods The clinical data of the 90 TM patients in Zibo Central Hospital from January 2013 to June 2017 was retrospectively analyzed. According to the results of ultrasonography, there were divided into the classical testicular microlithiasis group(CTM group, n=50) and the restricted testicular microlithiasis group(LTM group, n=40). Meanwhile, 50 males for routine health examination and without TM were randomly selected as the control group. The semen of three groups was collected to observe the difference in semen quality. Results There was no statistically significant difference in testicular resistance index among the three groups(P>0.05). There was statistically significant difference in the peak of systolic velocity(PSV) between CTM group, LTM group and control group(P<0.05). There was no significant difference in sperm volume and deformity rate among the three groups(P>0.05). Compared with the control group, the sperm quality of TM group decreased as a whole. In addition, there were significant differences in sperm density, sperm motility, positive motile sperm rate(PR), nonpositive motile sperm rate(NP) and inmotile sperm rate(IM) between CTM group and LTM group(all P<0.05). Conclusions Testicular microlithiasis can affect the sperm quality of adult males and the sperm quality of CTM group is significantly lower than that of LTM group.