磁共振对AIDS合并神经梅毒患者的诊断价值及其成像特点分析

Diagnostic value and imaging characteristics of magnetic resonance imaging in patients with AIDS complicated with neurosyphilis

目的探究磁共振对获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)合并神经梅毒患者的诊断价值及其成像特点。方法选取杭州市西溪医院2016年1月至2018年12月诊治的128例AIDS疑似合并神经梅毒患者,所有患者均进行磁共振成像检测,分析磁共振对AIDS合并神经梅毒的诊断价值及其成像特点。结果本研究中,128例患者经实验室病理学检测确诊,AIDS合并神经梅毒76例,影像学诊断结果显示,阳性69例,阴性7例;单纯AIDS患者52例,影像学诊断结果显示,阳性4例,阴性48例,即,真阳性69例、假阳性4例、真阴性48例、假阴性7例。检测灵敏度90.79%,特异度92.31%,约登指数83.10%;本研究合计76例AIDS合并神经梅毒患者,共检出4种表现型,分别为脑膜血管型、脑实质型、树胶肿型及脊髓型。结论磁共振对AIDS合并神经梅毒具有一定的诊断价值,有助于本病的早期发现、诊断及临床分型。

Objective To investigate the diagnostic value and imaging characteristics of magnetic resonance imaging in patients with acquired immunodeficiency syndrome(AIDS)complicated with neurosyphilis.Methods A total of 128 patients with AIDS and suspected neurosyphilis admitted to our hospital from January 2016 to December 2018 were enrolled.All patients underwent magnetic resonance imaging to observe the diagnostic value of magnetic resonance imaging in patients with AIDS complicated with neurosyphilis and to analyze its imaging characteristics.Results In this study,128 patients were diagnosed by laboratory pathology,76 cases of AIDS complicated with neurosyphilis,and the results of imaging diagnosis showed that 69 cases were positive and 7 cases were negative.In 52 cases of simple AIDS patients,the results of imaging diagnosis showed 4 cases were positive and 48 cases were negative,which indicates 69 cases were true positive while 4 cases were false positive,and 48 cases were true negative,while 7 cases were false negative.The sensitivity of detection was 90.79%,the specificity was 92.31%,and the Yoden index was 83.10%.In this study,76 patients with both AIDS and neurosyphilis were detected,and 4 phenotypes were detected,including meningeal vascular type,brain parenchyma type,gum type and spinal cord type.Conclusions Magnetic resonance imaging has certain diagnostic value for AIDS with neurosyphilis,which is helpful for the early detection,diagnosis and clinical classification of this disease.