摘要
Background and aim:Progressive muscle relaxation(PMR)is one of the most common complementary and alternative therapies.Published systematic review unfolded that PMR has a positive impact on chemotherapy-induced nausea and vomiting among adult cancer patients.However,the pooled findings were not reliable and valid because included trials have poor quality.It must be noted is that additional studies with good quality have been published recently.So,we design this updated systematic review to comprehensively establish the efficacy of PMR for the of chemotherapy-induced nausea and vomiting among cancer patients.Methods:We will search PubMed,Cochrane Controlled Register of Trial(CENTRAL),Cumulative Index to Nursing and Allied Health Literature(CINAHL),China Biomedical Literature database(CBM),China National Knowledge Infrastructure(CNKI),and Wanfang data to capture all potential items.Data extraction sheet will be used to extract all essential information,the Cochrane risk of bias assessment tool will be utilized to appraise the risk of bias of eligible studies.Finally,a quantitative analysis will be performed if sufficient data were obtained.In contrast,a qualitative analysis will be used to summarize the results of all included studies.Ethics and dissemination:Ethics approval and patient written informed consent will not be required because all of the analyses in the present study will be performed based on data from published studies.We will submit our systematic review and network meta-analysis to a peer reviewed scientific journal for publication.
背景与目的:渐进性肌肉放松(PMR)是最常见的补充和替代疗法之一。公开的系统评价表明,PMR对化疗引起的成年癌症患者的恶心和呕吐具有积极影响。但是,合并的结果不可靠且无效,因为纳入的试验质量较差。必须指出的是,最近已经发表了的高质量其他研究。因此,我们设计了此更新的系统评价,以全面确定PMR有预防和缓解癌症患者化疗引起的恶心和呕吐的功效。方法:我们将搜索PubMed,Cochrane对照试验登记册(CENTRAL),护理和相关健康文献的累积索引(CINAHL),中国生物医学文献数据库(CBM),中国国家知识基础设施(CNKI)和万方数据库,以捕获所有数据潜在项目。数据提取表将用于提取所有基本信息,Cochrane偏倚风险评估工具将用于评估合格研究的偏倚风险。最后,如果获得足够的数据,将进行定量分析。相反,将使用定性分析来总结所有纳入研究的结果。伦理与传播:由于本研究中的所有分析均将基于已发表研究的数据进行,因此不需要伦理学批准和患者书面知情同意。我们将把我们的系统评价和网络荟萃分析提交给同行评审的科学期刊以供出版。
