扩展高频在多囊卵巢综合征患者早期听损伤检测中的应用

The application of extended high frequency audiometry in detecting the early hearing loss for polycystic ovarian syndrome

目的:初步探讨扩展高频用于评估多囊卵巢综合征(PCOS)患者早期听损伤的临床意义。方法:对40例确诊的年轻PCOS患者和20例健康对照者进行传统常规频率(0.25~8.00 kHz)和扩展高频(10~20 kHz)纯音听阈测试,并对其结果进行统计学分析。结果:2组的听力阈值在0.25、0.50、1.00、2.00和4.00 kHz的频率下相似,差异无统计学意义(P>0.05);PCOS组在8~20 kHz频率下的听阈均显著高于对照组,差异有统计学意义(P<0.05)。PCOS组的扩展高频检出率低于对照组,以16、18 kHz最为明显,差异有统计学意义(P<0.05)。结论:PCOS患者早期的听损伤从扩展高频开始,扩展高频在PCOS早期听损伤评估中较常规频率纯音测听更敏感。

Objective:To preliminarily explore the clinical significance of extended high frequency audiometry in evaluating the early hearing loss in patients with polycystic ovarian syndrome(PCOS).The results were statistically analyzed.Method:The hearing threshold of forty young women diagnosed as PCOS and 20 healthy controls were obtained by using conventional audiometry(0.25-8.00 kHz)and extended high frequency(10-20 kHz)pure tone audiometry.Result:The hearing thresholds of the two groups were similar at conventional frequencies of 0.25,0.50,1.00,2.00 and 4.00 kHz(P>0.05).The hearing threshold of PCOS group at 8-20 kHz frequency was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).The expanded high-frequency detectable rate was lower in PCOS group than that in control group,especially at 16 and 18 kHz(P<0.05)and the differences were statistically significant.Conclusion:The early hearing impairment of PCOS patients starts from the extended high frequency,which is more sensitive than the conventional pure tone audiometry in the early hearing impairment assessment of PCOS patients.