摘要
造血干细胞移植是治愈血液系统恶性肿瘤、造血衰竭性疾病和先天性遗传性代谢性疾病的重要方法。脐血是造血干细胞的主要来源之一,是干细胞研究及应用最理想的细胞来源。本文从脐血移植的历史及现状、脐血移植的优势、脐血移植技术的改进、脐血移植的应用前景及展望等方面,对脐血移植30多年的临床应用进行回顾和展望。
Hematopoietic stem cell transplantation is a pivotal method to treat hematological malignancies,hematopoietic failure diseases and inherited metabolic diseases.Umbilical cord blood is one of the main sources of hematopoietic stem cells and the most ideal cell source for stem cell research and application.In this article,the clinical application of umbilical cord blood transplantation for more than 30 years was reviewed from the aspects of the history,current situation,advantages,improvement,application prospect and expectation of umbilical cord blood transplantation.
作者
孙自敏
Sun Zimin(Department of Hematology,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230001,China)
出处
《器官移植》
CAS
CSCD
北大核心
2020年第2期199-203,共5页
Organ Transplantation
基金
国家自然科学基金面上项目(81470350)
中央高校基本科研业务费专项资金(WK9110000001)。
关键词
脐血移植
移植物抗宿主病
造血干细胞移植
血液系统恶性肿瘤
造血衰竭性疾病
白血病
干细胞
复发
Umbilical cord blood transplantation
Graft-versus-host disease
Hematopoietic stem cell transplantation
Malignant tumor of blood system
Hematopoietic failure disease
Leukemia
Stem cell
Recurrence
