人工光合作用介导的辅酶再生研究进展

Advances in photosynthesis for coenzyme regeneration

人工光合作用是通过模拟自然光合作用将太阳能转变为化学能的过程,其研究领域主要集中在水裂解、CO2固定和辅酶再生这三方面。辅酶是大部分氧化还原酶催化反应中的关键辅助因子,在工业生产中用量极大,具有十分重要的价值。然而,辅酶的生产和提纯成本极高,导致其价格高昂,应用受阻。人工光合作用可以利用太阳能进行辅酶再生,有望通过辅酶循环利用的方法降低工业中生物催化反应成本。本文中,笔者系统地阐述人工光合作用及辅酶再生的机制,总结近年来用于辅酶再生的人工光合系统的研究进展,并对人工光合作用在辅酶再生领域的未来趋势进行展望。

Artificial photosynthesis(APS)is a process to convert solar energy into chemical energy by mimicking natural photosynthesis(NPS),covering on the fields of water splitting,carbon dioxide fixation and coenzyme regeneration.Coenzymes are the critical cofactors for the function of most oxidoreductases,crucial in industrial processes.However,the production and purification cost of redox-active coenzyme is extremely high,resulting in high price and limited application.Artificial photosynthesis achieves.coenzyme regeneration through utilizing solar energy,and this solar energy-induced coenzyme recycling is a promising way to decrease the cost of industrial biocatalysis.In this review,we systematically introduce the mechanism of both artificial photosynthesis and coenzyme regeneration,then summarize the research progress of this field in recent years.Finally,we address the trend of artificial photosynthesis induced coenzyme regeneration.