子宫动脉栓塞术治疗症状性子宫肌瘤的疗效及对卵巢功能的影响分析

Analysis of the effect of uterine artery embolization on symptomatic uterine leiomyoma and its effect on ovarian function

目的:探讨子宫动脉栓塞术治疗症状性子宫肌瘤的疗效及对卵巢功能的影响。方法:2017年7月-2018年6月收治症状性子宫肌瘤患者28例,均接受子宫动脉栓塞术(UAE)治疗;比较患者在治疗前及治疗3个月、6个月和12个月后的子宫、肌瘤体积及卵巢内分泌功能的各项指标,并与正常体检组的相应指标进行比较。结果:患者治疗后,术后3个月季、6个月和12个月后子宫体积、肌瘤体积均显著缩小,并呈现逐渐缩小的态势,每次检测变化比较,差异有统计学意义(P<0.05)。患者治疗后,各项卵巢功能变化指标与治疗前比较,差异无统计学意义(P>0.05);与正常组比较,差异无统计学意义(P>0.05)。结论:子宫动脉栓塞术疗法治疗症状性子宫肌瘤效果较稳定,对子宫、卵巢造成的负面影响相对较小,能够较好地保护卵巢功能。

Objective:To investigate the effect of uterine artery embolization on symptomatic uterine leiomyoma and its effect on ovarian function.Methods:28 patients with symptomatic uterine leiomyoma were selected from July 2017 to June 2018,all patients received uterine artery embolization(UAE)treatment.The volume of uterus and myoma and the indexes of ovarian endocrine function were compared before and after treatment for 3 months,6 months and 12 months,and compared with the corresponding indexes of the normal physical examination group.Results:After treatment,the volume of uterus and leiomyoma decreased significantly 3 months,6 months and 12 months after operation,and showed a trend of gradual reduction.The difference was statistically significant between each test change(P<0.05).After treatment,there were no statistically significant differences in various ovarian function indicators before treatment,three months,six months,and one year later(P>0.05),compared with the normal group,the differences were not statistically significant(P>0.05).Conclusion:Uterine arterial embolization therapy is more stable in the treatment of symptomatic uterine fibroids,and has relatively less negative effects on the uterus and ovaries,which can better protect ovarian function.