单采血小板联合冷沉淀治疗急性大出血患者的疗效分析

Analysis of efficacy of single platelet extraction combined with cold precipitation in the treatment of acute hemorrhage

目的:分析急性大出血患者以冷沉淀、血小板联合治疗的有效性。方法:取2016年5月~2018年7月期间125例急性大出血者为研究对象,按数字表法随机分组,A组41例(输入单采血小板)、B组42例(输入冷沉淀)、C组共42例(血小板+冷沉淀),比较凝血指标治疗前后水平变化,组间比较患者24 h止血有效率,统计各组止血时间及血小板、冷沉淀、红细胞输注量情况。结果:输注后C组PT、APTT水平低于其他两组,差异有统计学意义(P<0.05);C组血小板、冷沉淀输注量少,24 h止血有效率高、止血用时短,差异有统计学意义(P<0.05)。结论:对急性大出血者行血小板、冷沉淀联合输注,临床止血效果理想,患者凝血功能得到改善,止血用时短。

Objective To analyze the efficacy of combined treatment of cold precipitation and platelet in acute haemorrhagic patients.Method 125 cases of acute major hemorrhage from May 2016 to July 2018 were taken as subjects and randomly grouped according to the numerical table method.A group had a total of 41 cases(input platelet alone),B group had a total of 42 cases(input cold precipitate),and C group had a total of 42 cases(platelet+cold precipitate).The changes in levels before and after coagulation index treatment were compared.The group compared patients with 24 h hemostatic efficiency.The time of hemostasis,platelet,cold precipitation and erythrocyte infusion were counted.Results After infusion,the level of PT and APTT in Group C was lower than that of the other 2 groups(P<0.05);Group C had less platelet and cold precipitate infusion,high hemostasis efficiency and short hemostasis time(P<0.05).Conclusion The combined transfusion of platelets and cold precipitates in patients with acute major hemorrhage has a good effect on hemostasis,improved coagulation function,and short time for hemostasis.