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英夫利西单抗联合硫唑嘌呤片治疗炎症性肠病的疗效观察 被引量:3

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摘要 目的观察英夫利西单抗联合硫唑嘌呤片治疗炎症性肠病的疗效。方法选取收治的102例炎症性肠病患者,随机分为对照组和观察组组各51例。对照组予以英夫利西单抗治疗,观察组在对照组基础上加用硫唑嘌呤片治疗,比较两组临床疗效、症状变化、T淋巴细胞水平。结果与对照组相比,观察组总有效率较高,差异有统计学意义(P<0.05);与治疗前相比,两组治疗14周后CAI评分均降低,且观察组较对照组低,差异有统计学意义(P<0.05);与治疗前相比,两组治疗14周后CD3^+、CD4^+、CD8^+水平均升高,CD4^+/CD8^+水平降低,且观察组较对照组变化明显,差异有统计学意义(P<0.05)。结论炎症性肠病采用英夫利西单抗联合硫唑嘌呤片治疗可有效缓解病症,调节T淋巴细胞亚群水平,提高治疗效果,促进患者康复。
作者 赵新艳
机构地区 荥阳市人民医院
出处 《现代诊断与治疗》 CAS 2019年第22期3924-3925,共2页 Modern Diagnosis and Treatment
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