儿童荨麻疹的发病机制和诊治进展

The Pathogenesis,Diagnosis and Treatment of Urticaria in Children

荨麻疹是一种常见的皮肤病,约15%-20%的人至少发生过一次荨麻疹。尊麻疹发病机制复杂,直至目前也尚未明确,已知真皮肥大细胞的活化和脱颗粒在其中发挥关键性作用。儿童荨麻疹的发病率远低于成人且通常为自限型,即使该病有病程短、非致命性等临床特点,但对患者身体和心理影响较大,尤其是对儿童患者。现对儿童荨麻疹的发病机制、诱因、诊断和治疗的进展做一综述。

Urticaria is a common skin disease that 15%〜20%people have urticaria at least one time.The pathogenesis of urticaria is complex,which has not been clarified until now.The activation and degranulation of dermal mast cells are known to play a key role.Urticaria is much less common in children than in adults and is usually selflimiting.Although the disease has a short course,non-lethal and other clinical characteristics,the physical and psychological impact are more severe,especially on children.This article reviews the pathogenesis,inducement,diagnosis and treatment of urticaria in children.