保乳手术与改良根治术治疗早期乳腺癌的临床比较

Comparison of breast conserving operation and modified radical operation in the treatment of early breast cancer

目的比较保乳手术与改良根治术的优势。方法采用前瞻性研究方法,选择2016年10月~2018年12月就诊于本院并接受相应治疗的早期乳腺癌作为研究对象,将患者分为保乳组(n=36)和改良根治组(n=36),观察记录手术相关指标、术后并发症;生活质量并对比分析。结果两组患者基线特征的差异没有统计学意义(P<0.05)。保乳组在手术时间、手术出血量、引流量、住院时间、乳房美观性优于改良根治组,比较有统计学意义。两组患者的功能量表评分相比无差异(P>0.05),在比较两组疲劳、呕吐、疼痛、失眠、财政困难、乳房症状、脱发症状发生率,差异具有统计学意义(P<0.05)。两组经济条件、复发恐惧、形象影响、生育愿望相比存在统计学意义(P<0.05),保乳组对复发的恐惧高于根治组(P<0.05)。结论保乳手术在治疗早期乳腺癌的手术选择方面具有优势,这符合以往的研究报告。

Objective To compare the advantages of breast conserving operation and modified radi⁃cal operation.Methods This is a prospective research method.The early breast cancer patients who were treated in our hospital from October 2016 to December 2018 were selected as research objects.The patients were divided into two groups:breast conserving operation group(n=36)and modified radical op⁃eration group(n=36).The relevant indexes,postoperative complications,quality of life were observed and analyzed.Results There was no significant difference in baseline characteristics between the two groups(P<0.05).Compared with the modified radical mastectomy group,the operation time,bleeding volume,drainage volume,hospitalization time and breast aesthetics of the breast conserving group were significantly better.There was no difference in functional recovery score between the two groups(P>0.05),however,there were significant differences in the incidence of fatigue,vomiting,pain,insom⁃nia,financial difficulties,breast symptoms and hair loss between the two groups.There were significant differences between the two groups in terms of economic conditions,fear of recurrence,image influence and fertility desire(P>0.05),but the fear of recurrence in breast conserving group was higher than that in radical group(P<0.05).Conclusion Breast conserving surgery has advantages in the choice of sur⁃gery for early breast cancer,which is in line with previous research reports.