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吉非替尼联合放疗治疗非小细胞肺癌脑转移的效果及不良反应率观察 被引量:2

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摘要 目的:观察吉非替尼联合放疗治疗非小细胞肺癌脑转移的效果及不良反应率。方法:从2017年4月到2018年4月期间我院诊疗的非小细胞肺癌脑转移患者74例为研究对象,采用随机数字法分为常规组和联合治疗组2组,给予常规组(n=37例)全脑放疗方法进行治疗,给予联合治疗组(n=37例)吉非替尼联合放疗治疗。观察2组患者临床治疗总有效率、不良反应发生概率、6个月生存率、1年生存率的差异性。结果:联合治疗组临床治疗有效率为64.86%,明显高于常规组(p<0.05);联合治疗组不良反应发生概率为10.81%,明显低于常规组(p<0.05);联合治疗组3个月生存率81.08%、6个月生存率62.16%、1年生存率51.35%,均明显低于常规组(p<0.05)。结论:相比单独采用全脑放疗方法治疗而言,吉非替尼联合放疗治疗非小细胞肺癌脑转移的效果更加显著,能够明显降低不良反应发生率,提高生存率,可在临床上推广应用。
作者 谢阳
出处 《黑龙江中医药》 2019年第6期136-137,共2页 Heilongjiang Journal of Traditional Chinese Medicine
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