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妊娠滋养细胞肿瘤药物治疗研究进展 被引量:13

Research progress in drug treatment for gestational trophoblastic neoplasia
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摘要 妊娠滋养细胞肿瘤(gestational trophoblastic neoplasia,GTN)是一组与妊娠相关的恶性肿瘤,组织学上来源于胎盘滋养细胞,分为侵袭性葡萄胎(invasive mole,IM)、绒毛膜癌(choriocarcinoma,CC)、胎盘部位滋养细胞肿瘤(placental site trophoblastic tumour,PSTT)和上皮样滋养细胞肿瘤(epithelioid trophoblastic tumour,ETT)。
作者 向阳 蒋芳 XIANG Yang;JIANG Fang
机构地区 中国医学科学院
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2020年第1期25-28,共4页 Chinese Journal of Practical Gynecology and Obstetrics
基金 国家自然科学基金(81971475) 中国医学科学院医学与健康科技创新工程(2017-I2M-1-002)。
关键词 妊娠滋养细胞肿瘤 分层治疗 免疫治疗 靶向治疗 gestational trophoblastic neoplasia stratified therapy immunotherapy targeted therapy
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  • 1Seckl M J, Sebire NJ, Berkowitz RS.Gestational trophoblastic dis- ease [ J ]. Lancet,2010,376(9742):717-729.
  • 2Berkowitz RS, Goldstein DP.Chorionic tumors [J ]. N Engl J Med, 1996,335 (23): 1740-1748.
  • 3Ngan HY, Kohoru El, Cole LA, et al.Trophoblastic disease [J]. Int J Gynaecol Obstet,2012,119 Suppl 2:S 130-136.
  • 4Taylor F, Grew T, Everard J, et al.The outcome of patients with low risk gestational trophoblastic neoplasia treated with single agent intramuscular methotrexate and oral folinic acid [J ]. Eur J Cancer,2013,49(15):3184-3190.
  • 5Sita-Lumsden A, Short D, Lindsay I, et al.Treatment outcomes for 618 women with gestational trophoblastic tumours following a molar pregnancy at the Charing Cross Hospital, 2000- 2009[J ]. Br J Cancer,2012,107(11):1810-1814.
  • 6Chalouhi GE, Golfier F, Soignon P, et al.Methotrexate for 2000 FIGO low-risk gestational trophoblastic neoplasia patients: effi- cacy and toxicity [J ]. Am J Obstet Gynecol,2009,200(6):643 e l- e6.
  • 7Chapman-Davis E, Hoekstra AV, Rademaker AW, et al.Treat- ment of nonmetastatic and metastatic low-risk gestational tro- phoblastic neoplasia: factors associated with resistance to sin- gle-agent methotrexate chemotherapy [J]. Gynecol Oncol,2012, 125(3):572-575.
  • 8Kang WD, Choi HS, Kim SM.Weekly methotrexate (50mg/m(2)) without dose escalation as a primary regimen for low-risk gesta- tional trophoblastic neoplasia [J]. Gynecol 0ncol,2010,117(3): 477-480.
  • 9Gilani MM, Yarandi F, Eflekhar Z, et al.Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low- risk gestational trophoblastic neoplasia [J]. Aust N Z J Obstet Gynaecol,2005,45 (2): 161 - 164.
  • 10Osborne RJ, Filiaci V, Sehink JC, et al.Phase III trial of week- ly methotrexate or pulsed dactinomycin for low-risk gestational trophoblastic neoplasia: a gynecologic oncology group study [ J ]. J Clin Oncol,2011,29(7):825-831.

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