根治性前列腺切除术在盆腔淋巴结受侵及转移性前列腺癌中的应用及现状

Application and present situation of radical prostatectomy in patients with pelvic lymph node positive disease and metastatic prostate cancer

前列腺癌为临床常见泌尿系肿瘤,该疾病具有很高的侵袭性,大多数前列腺癌患者在初诊时已经出现转移。传统观念认为盆腔淋巴结受侵及转移性前列腺癌患者应当选择全身系统性治疗,不推荐根治性前列腺切术。近年来,随着技术手段的进步,经过筛选,一些患者接受了根治手术并达到了良好的生存获益效果。根治性前列腺切术应用于盆腔淋巴结受侵及转移性前列腺癌这一新的理念逐渐被临床医师所重视。为此,本文对根治性前列腺切除术在盆腔淋巴结受侵及转移性前列腺癌中的应用及现状作一综述。

Prostate cancer is a common urinary system disease and a very aggressive malignancy.Most patients are presented with metastasis at diagnosis.Traditionally,systematic treatment was recommended in patients with pelvic lymph node positive disease and metastatic prostate cancer.Radical prostatectomy was discouraging.In recent years,with the development of treatment method,some cases underwent radical prostatectomy and achieved positive outcomes.Radical prostatectomy used in patients with pelvic lymph node positive disease and metastatic prostate cancer,a new concept,is gaining more and more attention.Thus,the purpose of this review was to summarize the current knowledge on radical prostatectomy in this setting.