微创抽吸引流术联合阿替普酶治疗脑出血的疗效

Efficacy of minimally invasive aspiration and drainage combined with ateplase in the treatment of intracerebral hemorrhage

目的分析颅内血肿微创抽吸引流术联合阿替普酶治疗自发性脑出血的临床效果。方法将我院收治的自发性脑出血患者60例,随机分为观察组和对照组,每组30例。对照组给予保守治疗,观察组在此基础上给予颅内血肿微创抽吸引流术联合阿替普酶治疗,比较两组血肿量、住院时间、出院时格拉斯哥昏迷评分(GCS)、格拉斯哥预后评分(GOS)及出院后1个月日常生活能力评分(ADL)。结果观察组治疗后1 d、3 d、7 d血肿量低于对照组(P<0.05);观察组住院时间短于对照组,出院时GCS评分、GOS评分高于对照组(P<0.05);观察组出院后1个月ADL评分高于对照组(P<0.05)。结论颅内血肿微创抽吸引流术联合阿替普酶治疗自发性脑出血患者,能促进患者颅内血肿的清除,缩短住院时间,改善患者意识状态与预后,提高患者日常生活能力。

Objective To analyze the clinical effect of minimally invasive aspiration and drainage combined with ateplase in the treatment of spontaneous intracerebral hemorrhage.Methods 60 patients with spontaneous intracerebral hemorrhage admitted to our hospital were randomly divided into the control group and the observation group,30 cases in each group.The control group was given conservative medical treatment and the observation group was given minimally invasive aspiration and drainage combined with ateplase treatment on this basis of control group.The amount of hematoma,hospitalization time,the Glasgow Coma Score(GCS)on discharge,Glasgow Prognosis Score(GOS)and score of Activity of Daily Life Scale(ADL)1 month after discharge were compared between the two groups.Results The amount of hematoma in the observation group was lower than that in the control group 1 day after treatment,3 days after treatment and 7 days after treatment(P<0.05);the hospitalization time in the observation group was shorter than that in the control group;the GCS score and GOS score on discharge were higher than those in the control group(P<0.05);and the ADL score in the observation group was higher than that in the control group 1 month after discharge(P<0.05).Conclusion Minimally invasive aspiration and drainage combined with ateplase in the treatment of spontaneous intracerebral hemorrhage can promote the clearance of intracranial hematoma,shorten hospitalization time,improve patients’consciousness and prognosis,and improve patients’daily living ability.