1例新生儿血小板减少伴真菌感染临床治疗的药学监护

Pharmacological Care in Clinical Medication of a Case of Neonatal Thrombocytopenia Complicated with Fungal Infection

目的:分析临床药师在新生儿血小板减少伴有真菌感染的治疗中开展药学监护的切入点,探究其药学监护过程。方法:根据新生儿的病理生理特点及目前国内外最新相关诊疗指南,临床药师参与1例新生儿血小板减少伴真菌感染临床治疗的全过程,协助临床医师为患儿制定个体化的药物治疗方案,并对患儿的病情变化提出药学建议以及对患儿开展全面的药学监护。结果:临床药师对新生儿血小板减少伴真菌感染,结合新生儿的特殊病理生理特点,实施全面的药学监护,以抗菌药物的用药安全与合理使用、药品不良反应的监测等方面作为药学监护的切入点,提供患者个体化的药学服务。结论:在日常工作中,临床药师能够结合自身专业知识通过开展药学监护参与临床诊疗工作,极大地促进了临床药物的安全、合理和有效使用。

Objective:To analyze the entry point of pharmaceutical care by clinical pharmacists in the treatment of neonatal thrombocytopenia with fungal infection,and to explore the process of pharmaceutical care.Methods:According to the pathophysiological characteristics of neonates and the latest relevant guidelines for diagnosis and treatment at home and abroad,the clinical pharmacist participated in the whole process of treatment of a case of neonatal thrombocytopenia complicated with fungal infection,and assisted the clinician in formulating individual drug treatment plan for the patient.Based on the change of the condition of the child,the pharmaceutical suggestion is put forward,the adverse reaction of the medicine is monitored and and the comprehensive pharmaceutical monitoring of the child is carried out.Results:The clinical pharmacist conducted comprehensive pharmacological monitoring of the course of treatment of the neonatal thrombocytopenia complicated with fungal infection.Through taking the point of the safety and rationality of the use of antimicrobial agents,as well as the monitoring and management of adverse drug reactions,the clinical pharmacist provides individualized pharmaceutical care for the patient combining with the special pathophysiological characteristics of neonates.Conclusion:The clinical pharmacists can participate in the clinical diagnosis and treatment by carrying out the medical monitoring in combination with the professional knowledge,and they greatly promote the safe,reasonable and effective use of the clinical medicine during the day-to-day work.